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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aefbbc58c286d44ba66a88d6b36443b576da696e85b8f214f7286a7461ceb72b' 
  AND token = 'HCwb6vx/xQH+iiosMp+EIj97n+Gf9y91qMCX1c+F2iM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}