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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '277463d5f90a9d7cd257143e0fa8e63a023234be9fb657138c3bd5584a8c961d' 
  AND token = 'muc5DfJcTqn/7wt92Ye8wxuEdmJKSugbG2k8G8KmRKA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}