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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d566d4d83d40d67679f1e94b36f229a7d25cde17d6298589b712d381fd000e0' 
  AND token = 'h66IWmxCo5Ubh9RCte89z6LJ2JF+t1wwfBkn8HLtiJo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}