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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '246531ba4767f3c7995f1a43c00c084897ef89574d511f5400c1a08ce40d364f' 
  AND token = '4q5Pf3ztPtc+zteMsordD/m+cgGj9Wa17qtqBQl0zqI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}