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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f4b8e32055d46758e546246db6215c2cd89a105e1e56f9e8d2ffdfcf89e2314' 
  AND token = 'NaRQodtA9IkATKIDZBj1HYKHWUfx8qJ3gAlLOg4y+F0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}