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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '79b580e0f157b2ff4c7650f33e159c1be675e53110d1e7219d7aca9f60c5e7f4' 
  AND token = 'AoFiF7FqwHSvruW2JGFB3NXykboKmjkYlGfG6fNZ/1M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}