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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c44fcce4db001bcd59eb59c6c521251ac36ade9269de20d001a1c8666d14ee4e' 
  AND token = 'dxq89pyq1p3zkumS/3gsekmf4AydMuRZ8ndJ7u3lpdY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}