SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b57f3dee08591ee08fc213fcaec641f64c5a9a79e86d6a1e0e1608397f868ef' 
  AND token = '4rTcAiz1urreCAoB6ZgG7ui9jNFKyB/tIWSf2z0ECl8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}