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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b85b3eb21cb4fc7b388db73c43fd9bc0f8ea26491f2906556f8eff20c3209b02' 
  AND token = 'fS4i34a8RbSphJHFUHXI+jf1KeCpv4K0lErC/SPThUs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}