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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25bd125f84876b047606167c6a7bdca0b81c0f1edb315bd11c85bb2770ea48e9' 
  AND token = 'JknSGZ6BLoRH/Nrsl7kGPgT4qWi12k/vB2ZwEM9aahw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}