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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '329945fe067bf1e5fae12b7bfe72f438e44203818bb27c4e719d6f62128ba088' 
  AND token = 'KFx+2ar0o2Z2FvTlKX9gViViaYbtVs9D39s/TxfoKiQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}