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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'deb176cd0124511a7feb5d1d93ba1407bab522c5651c0218cf35fcfaa482cd22' 
  AND token = '++UE75ACmAKniDpkHzCt0mEqKSTFbjDs8iZJZk+lFvA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}