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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3dd112c05ebc39ad663d5047adc9b359034c6f5c38e3b74186f3fb5e513ae68d' 
  AND token = 'DIuTqdd6p6UtsZOKrYiU6kgybMK6T4MbF1z31dbD+Tg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}