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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a4f0529ed1f4a6f63e211d16c9a6c4c5aaa32c53d1b0452db6afa7f431e0464' 
  AND token = 'stX8zRnNdgZf6vn5w2bOgkFTxw7IvEYWMe8vzEdKAS8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}