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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '674cba9fc78a52ab3f632e98ce370532577c70731ff1b01d0a3bf04cc7b8d15f' 
  AND token = 'R8nAuldkTWHACUa0gXTNuNuzYKCI8R+ddlwGL6WO1A8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}