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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '164de1a4580e6d5afce81d3c022269e711c74ed1adeeb108c875a49af1d97d04' 
  AND token = 'dYs6FjrYaumV/c4ZyNbqWBe0tQny5FDhmYUIKLaOdbM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}