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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d22ed838944ae1191ed1edefae53961efd1195860c539d8ebd1fc334582dc48' 
  AND token = 'Le07ru0/BdQHHHqv/D4pFspNMlG2NtduTBk+3HsxSnE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}