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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50c6b5a6037638f05dcef4189c5d7c2a281dedaf910ac400fbd4c63b68a09ec4' 
  AND token = 'Ttfy96Cn6198PQ66QV3RByjHcXdJcgimipD5tdb1vtQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}