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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2a21c8542fb7e717831adc20d2a037394346f1607dd97f2e70cf8f0551fb829' 
  AND token = 'SvAw4jpcZ7PFe0SwTAQ1+7K1vxzO7Ae2oKOx3CHN8og=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}