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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c049e1f6cd91d4d5c9046d1543cd6553c59a6019b5be882b8e88de80fa7ce7d6' 
  AND token = 'B5tGgNqGc11h0ly1XWYqPOvlzpZVITferfCGPp7dBy8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}