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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00f313f7fba2fc14aa2c0f50644ec965ff5f3f278b6ce399d911346d558ee021' 
  AND token = '+v2DczqdA1vOK+qQZyQbqvp0BU5w/v35Lu6KetRDh9E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}