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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5b061f1cd8f0b0e3466f82aa01a8de9c09c77af764d5e7f77baf8e433c72b5f' 
  AND token = 'QQe+MgJYd71Uqaq7Q+P7180xuARWcXjDlcHze1JwYuI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}