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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66f812b8212b5c35c9630b868eb7f7402772b5b640a25802f7522ce77862e002' 
  AND token = 'V1rXAg2bC25ahuwa6p3g1vKeRcT+W+Z0Q3EJRZ3O7Hs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}