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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53b1dfdef9ad9be1f8d2cd9686f608662795e032f1f3c25ed62dae3900d16a12' 
  AND token = '+UOs1/6f5w6BfbXQDHibW+gN3exl6ZwzB8xYyERAHpU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}