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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0592e17ca61a813c25f49754f7989241055058833912c419a1c4fb83078c685d' 
  AND token = 'fFsScaVn1SiLUCv+l60fYgmw+bE3NvA8BYpl+4xiZIU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}