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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1bc018381b01d699f7c1fae3db7320629b609b220d986171468366bf83a011b' 
  AND token = 'd1WwbH+MS4skLGIgzC+LkrMkT7LLQhs7KtaTYsdgyUs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}