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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e8f6dcafd9dfb2f850cec1c3cea65028546445b7cd8ce9d194e925155c81f10' 
  AND token = 't/KB5EFExjLItO9QoqrPIb0KDPLeP4s4291VrSrnxwA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}