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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19b4cbfe7322e2df0847f87e4bfd8364dcbda891bb4783d835ae86eadab8a779' 
  AND token = 'imIo+/D+2kn5rdZRk1L5ZbFWq+co7qx7OZSAsrwL0Qs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}