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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fed8a790db3f304e9ba654bcf633da5fc0ef94881609f28c21bb37fac203252f' 
  AND token = 'kF9bRzA9eqfhyN3HYD/nuAMcVdrs9LZkZYbfASK4jVk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}