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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cbcfb1b3445743dc216c10a077fa99eea7801aee833f357af78d03ef9a48f558' 
  AND token = 'BUIfbMNf0+zxtm+t8uBN0gx1hOJOpu4E8wLg3xj+vXU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}