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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3fe6228106076017e2d5466b543204f50be1c4cd40bf188a8ddfecbc4164e163' 
  AND token = '45lZaMRUWmN/BRmt0YnoMgt2TY2gb9r7l1rJd8NhiXw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}