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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f86a8b55f78226911c583c30447b2e9fcffc53cf6e321cfbfbb33923ea743f3c' 
  AND token = 'Mph0A7NQBMxDwrzb8VsZSte1M2wIL+uans2xq7a16BQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}