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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c7cc88887a21f7cd4ae06436c8d700cfb7ac9c252d7e13059179a68716a7df1' 
  AND token = 'C6LMExxI++E/gvuPjd20sitgmeCtw4H58amhYx/TtKU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}