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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '47386fe97f091a4cfa2fcde334b8097350550aec87cb7194f90857a82741d14f' 
  AND token = 'OyRHiqnDgbbME6MirJy9vccyhAWah80B2jCmQ8a+A7Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}