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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '216cd489a92d87a7f080c17cb03b4c4e62b260063eb0d378afa88cc87838f0fa' 
  AND token = '8uJybyW7K8i9+EKk5wN6IJ1hGZealnFUf6/7lQPfRKk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}