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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01bef546b8398b328f0f456f9cde6ccafc0c0e75a4a087a8f6d6c1ae0738be27' 
  AND token = 'NaQd3DRqIpYuTEK8qhZmFdo7zAoOLJiPtt255K/qnl8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}