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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b51f9543f971ac9d901cf1f76b06a1ffbc1f20f27ddb6c2d5aeb6ae8b7544cd6' 
  AND token = 'VHnN+u6YJh9IeY5495D7att68F21zN2Il/ONabmBD8A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}