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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd9efb23666b3dbde9b5b0c5dafbfbae5f60a0b34f611b20a187a94cd4015a06f' 
  AND token = 'yb/GzbT4eIWVIWLPrCfLC5Qhb+sRGMP42vXS/PmmmwE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}