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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45bab96c6782556b5e9d34c2759acfd03c094e7601d1e23adf7fbaf6c9ece7a9' 
  AND token = '4Qel946j+S4n1YDNAJl1gdaK/Y5O1pYyzIvpY2z4gkk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}