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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b46fdc52a75bd432ad45790d90b477617a0afd240d92b3c8c3f91923109e90a' 
  AND token = '3bYG4phUXkgLdCvmbrtybueSker9rnhByjHVuiRvugw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}