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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b52f56a4d2f000b64cd2f012e083eb7b51dd284b565991f52ce32f7aa5a324a' 
  AND token = 'X5Hyxx5firfcE8km6+bb4U2RVJ3VlUXSAZi0Tws1MZw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}