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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25eacff4f0a0e0b8d5c519126d87d69196670414606c4d17c0252b0a87c1ae2b' 
  AND token = 'bMxHJdnCmILS3TC7dgVoUsOwOoVe+hWAusItsrmFzQI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}