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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7043d2201a961e2c3f44e7f45598b7ac1a8874977e9cdaed8509ce43f17e2040' 
  AND token = 'Xyhk9EQ7kaarPUNIgdKR5dC1/FCEcFbTc5U3I/3sPRw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}