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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51545724b747fc35276393ed47d116b4f7b1539a0da795022bb0c5e218cabbc8' 
  AND token = 'Y0HSLUmw1XdBCHkIXPaRXw6vKaIjH/2ryFW7WZ2olZA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}