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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8f32537d9eb9b9a008b58018f331930021d1281ad31f98037945b7182796e34' 
  AND token = 'z9lnN9XvVvu3QS56/cyZaXymIGXd7D4VSXo4WDmCjQc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}