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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b06b24b362a56eb3a2760c97f98538ca08c55ba6bb1c62cbabc023a4688ef7c' 
  AND token = 'PwR5POmVrW4/Fu7/e4smU/YG/clKUIeUrz6SIxBQY/U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}