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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b371a1b8d0c5b45147f5f53bfc135989e0f1b55de76d17374f97bb08ace99ddf' 
  AND token = 'uvpwSx2aplRviTw3/kWxfD6BV85e5c3q5Ssy3V6jAow=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}