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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd7e14b1b8892c5fa56276dceffce04bee2b7604fa6016adb00458822ad747d44' 
  AND token = 'NbsIbsw8jC2iMrFQU3gXyAkMwsC7zjL2nM/Pujly20g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}