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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb3533772bd96fd25356a4fc524273c22da835587f09c5176db01f046f7342a2' 
  AND token = 'MqJQAEr0AK60rjU02CEGrfeR+Dppt26enTd6u8V23RY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}