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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9de8fbd525d6e93f0dde975f8178f2b4e3c7342f70d3167242b7252dff7757ff' 
  AND token = 'gDp0Jvzc2MIPq00TDESB3ygFdxcsp8L28gspbf6jyPk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}